STUNNED SILENCE: GENE EXPRESSION PROGRAMS IN HUMAN CELLS INFECTED WITH MONKEYPOX OR VACCINIA VIRUS.


E3 ubiquitin ligase MARCH5 positively regulates Japanese encephalitis virus infection by catalyzing the K27-linked polyubiquitination of viral E protein and inhibiting MAVS-mediated type I interferon production

ABSTRACT Membrane-associated RING-CH-type finger (MARCH) proteins, a class of E3 ubiquitin ligases, have been reported to be involved in the infection of multiple viruses and the regulation of type I interferon (IFN) production.However, the specific role and mechanisms by which MARCH proteins influence Japanese encephalitis virus (JEV) infection re

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Journey to the other side of the brain: asymmetry in patients with chronic mild or moderate traumatic brain injury

Aim: Patients with chronic mild or moderate traumatic brain injury have some regions of skull bride and groom brain atrophy (including cerebral white matter) but even more regions of abnormal brain enlargement (including other cerebral regions).Hypothesis: Ipsilateral injury and atrophy cause the eventual development of contralateral compensatory h

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